Protect your cells – Carotenoid Complex
Background: Carotenoids first took center-stage as protector nutrients in the mid 1970’s when researchers at the US Department of Health and Human Services and the Centers for Disease Control and Prevention (CDC) identified their role in reducing the risk of disease25. National Cancer Institute researcher Regina Ziegler went on to reveal its connection to lung cancer prevention in 198626, and then showed a lower risk of cancer in those with the highest dietary intake of fruit and vegetable-derived carotenoids27,28. The National Health and Nutrition Examination Survey (NHANES) and other studies at the time found carotenoids also functioned in heart health and reduced the risk of heart disease29,30. Proof of benefit soon expanded to include eye health and visual acuity31 and immune function32.
GNLD Research: Research conducted on GNLD’s Carotenoid Complex has spanned more than 15 years. It started with the first ever proof of bioavailability of whole food-derived carotenoids33,34. USDA researchers went on to reaffirm its bioavailability and then demonstrated its cardio-protective35,36 and cellular protective powers37. This was followed by two more studies conducted by the USDA researchers showing Carotenoid Complex’s beneficial effects on immune capacity38,39. In 2001, GNLD researchers reaffirmed bioavailability across an even broader spectrum of dietary carotenoids40.
Latest Findings: Evidence supporting the importance of carotenoid intake for health benefits continues to mount. Concern by leading health authorities over insufficient carotenoid consumption has resulted in campaigns to increase awareness for higher levels of carotenoid intake41,42.
Heart and cardiovascular health: A 2004 study conducted by a team at the Harvard Medical School found that men in the top quintile with higher levels of serum carotenoids (including alphacarotene, beta-carotene, lycopene, lutein, and beta-cryptoxanthin) had a 40% decreased risk of ischemic stroke than those with the lowest serum levels.43 Similarly, a 2008 study of 559 men showed that increased intake of alpha and beta carotene from carrots equated to a 17% reduction in risk of cardiovascular (CVD) death.44 Swedish researchers in 2006 correlated consistently lower levels of the carotenoids lutein, zeaxanthin, and beta cryptoxanthin with coronary artery disease occurrence. The healthy controls had significantly higher levels of these carotenoids in their blood45.
Prostate health: Since the early nineties, scientific research has reported a connection between the carotenoid Lycopene and prostate cancer risk reduction. One study showed that Lycopene (from tomatoes) present in the diet 4 to 5 times per week, attributed to a 25% reduction in prostate cancer risk. The 2-year study found that an 82% increase in blood Lycopene levels corresponded with a 42% decrease in prostate-specific antigen (PSA) levels46.
Immune health: Swedish researchers in 2001 observed higher levels of natural killer cells (NK cells) in people with higher levels of these carotenoids, confirming the relationship between dietary carotenoid intake, immune capacity and health.
Vision health: In a 48-week intervention trial, researchers tested Lutein supplementation for vision protective-function in patients with retinitis pigmentosa (RP). They concluded: “Comparing the development of vision measures against the natural loss expected to occur over the course of the 48 weeks, most measures showed reduced decline, and these reductions were significant for normal illumination”47.
Mental performance: A2007 French study48 showed a connection between carotenoids and cognitive performance in a healthy elderly population. Study author Tasnime Akbaraly states “In this study, low levels of specific plasma carotenoids (lycopene and zeaxanthin) were associated to poor cognitive functioning in a highly educated, community-dwelling elderly population”.
Inflammatory health: A 2005 UK study by Cambridge University49 researchers showed that study subjects with the highest (top one third) daily intake of beta-cryptoxanthin had only about one-half the risk of developing polyarthritis than those in the bottom one-third. Researchers commented that even modest increases in beta-cryptoxanthin intake were associated with a significantly reduced risk of developing inflammatory disorders such as rheumatoid arthritis.
Pro Vitality Nutrition – Whole Food Nutrition for Lifelong Health and Vitality… in convenient, on-the-go packets
In my next post, we will look at another GNLD product that can help solve this health crisis:
Omega-III Salmon Oil Plus – Balance & Regulate your cells
In my previous post, we looked at another GNLD product that can help solve this health crisis:
Tre-en-en Grain Concentrates – Feed your cells
Carotenoid Complex – Protect your cells
26 Ziegler, R. G., et al; Carotenoid intake, vegetables, and the risk of lung cancer among white men in New Jersey; 1986, American Journal of Epidemiology, 123:1080-1093
27 Ziegler, R. G., A review of epidemiologic evidence that carotenoids reduce the risk of cancer. 1989. Journal of Nutrition. 119:116-122
28 Ziegler, R. G., Vegetables, Fruits, and carotenoids and the risk of cancer. 1991. Am. Jour. Clin. Nutr. 53:251S-259S
29 Verlangieri, A. J. et al; Fruit and vegetable consumption and cardiovascular disease mortality. 1985. Medical Hypothesis. 16:7-15
30 Rimm, E. B., et al: Dietary intake and risk of coronary heart disease in men. 1993, New England Journal of Medicine. 328:1450-1456
31 Knekt, P., et al; Serum antioxidant vitamins and risk of cataract. 1992. British Medical Journal. 305:1392-1394
32 Carotenoids in Human Health, 1993. Annals of the New York Academy of Sciences. 691:61-67
33 Carughi, A. & Hooper, FG. Plasma carotenoid concentrations beore and after supplementation with a carotenoid mixture. 1993. Annals of the New York
Academy of Sciences. 691:244-245
34 Carughi, A., Hooper, FG.; Plasma carotenoids before and after supplementation with a carotenoid mixture; American Journal of Clinical Nutrition 1994; Volume 59, pages 896-9
35 Z Dixon, B Burri, J Erdman, et al ; Effects of a carotene-deficient diet on measures of oxidative susceptibility and superoxide dismutase activity in adult women;; Free Radical Biology & Medicine, Volume 17, Number 6, pages 537-44
36 Y Lin, B Burri, et al; Effects of low dietary carotene intake on oxidative susceptibility in women; FASEB Journal, Volume 10, Number 3, page A478, April 1996
37 Z Dixon, B Burri, et al; Effect of low carotene diet on malondialdehyde (MDA) concentration; FASEB Journal, Volume 10, Number 3, page A240, April 1996
38 T Kramer, B Burri, et al; Carotenoid-flavonoid modulated immune response in women; FASEB Journal, Volume 9, Number 3, page A170, April 1995
39 T Kramer, B Burri, et al; Modulated mitogenic proliferative responsiveness of lymphocytes in whole-blood culture after a low-carotene diet and mixed carotenoid supplementation in women; American Journal of Clinical Nutrition
1997, Volume 65, pages 871-5
40 Carughi, A., Omaye, S., Furst, A.; Plasma carotenoid response to supplementation of a mix of fruits and vegetables; Proceedings of Experimental Biology, March 31 – April 4, 2001
43 Stroke. 2004; 35:1584-1588
44 2008, Journal of Nutrition: February, 138:344-350.
45 2006. Nutrition, Metabolism and Cardiovascular Disease.Published on-line: doi: 10.1016/numecd.2006.02.006
46 Urological Oncology (vol. 23, pp. 383-385)
47 Ophthalmology (BMC Ophthalmology 2006, 6:23)
48 The Journal of Gerontology: Medical Science; 2007; 3:308-316